Cold spray for reducing venopuncture pain in hemodialysis patients; a randomized double-blinded controlled trial

Zahra Shafii ¹ * , Neshiman Abdi Bastami ¹, Amir Ahmad Nasiri ²

Cited by CrossRef: 6

1- Alkhalidy A, Al-Jubouri M. Effect of Shot blocker and Cold Spray on Venipuncture Pain among Blood Donors: A Randomized Controlled Trial. Next Research. 2025;:100708 [Crossref]

2- Gürdap Z, Cengiz Z. Comparison of cold spray and shotblocker to reduce intramuscular injection pain: A randomized controlled trial. Clinical Pharmacy Therapeu. 2022;47(8):1249 [Crossref]

3- Sharifnia A, Chu G, Manias E, Davidson P, Fernandez R. Comparative analysis of the effectiveness of pharmacological and non-pharmacological interventions on arteriovenous fistula cannulation-related pain in patients receiving hemodialysis: A systematic review and network meta-analysis. International Journal of Nursing Studies. 2025;169:105123 [Crossref]

4- Ozen N, Akcoban S, Tosun B. Effect of cold needle application on the arteriovenous fistula cannulation-related pain: a self-controlled, double-blind study. Journal of Research in Nursing. 2025; [Crossref]

5- Arshad A, Ijaz U, Rafique B. Pharmacological interventions for pain management during arteriovenous fistula puncture in adults and adolescents undergoing maintenance haemodialysis: a systematic review. Ren Replace Ther. 2024;10(1) [Crossref]

6- Bedel C, Selvi F, Akçimen M. Vapocoolant Spray for Pain Control in Intramuscular Injection Applications: A Prospective, Randomized Controlled Trial. Ibnosina Journal of Medicine and Biomedical Sciences. 2022;14(02):068 [Crossref]

7- Lee K, Kim D, Lee H, Lee E. The effect of using vapocoolant spray for pain reduction in arteriovenous fistula cannulation among patients undergoing hemodialysis: A randomized control trial. Applied Nursing Research. 2023;71:151674 [Crossref]

8- Mahmoud H, Abdel Aziz S, Ibrahim M. Effect of cold application on intramuscular injection pain among patients with fractures. 2022;19(1):36 [Crossref]