Submitted: 14 Jan 2024
Accepted: 03 Jun 2024
ePublished: 29 Jun 2024
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J Nephropharmacol. 2024;13(2): e11674.
doi: 10.34172/npj.2024.11674
  Abstract View: 111
  PDF Download: 59

Case Report

Management of severe hyponatremia in a chronic kidney disease patient; a case report

Anass Qasem 1* ORCID logo, Syed Arman Rabbani 2 ORCID logo, Martin Thomas Kurian 1, Sathvik B Sridhar 2

1 Department of Nephrology, Ibrahim Bin Hamad Obaidullah Hospital, Ras Al-Khaimah, United Arab Emirates
2 Department of Clinical Pharmacy and Pharmacology, RAK College of Pharmacy, RAK Medical and Health Sciences University, Ras al Khaimah, United Arab Emirates
*Corresponding Author: Anass Qasem, Email: anass.qasem@ehs.gov.ae


Hyponatremia is a common electrolyte abnormality in chronic kidney disease (CKD). Managing severe hyponatremia in CKD is challenging, requiring the correction of biochemical imbalances and fluid overload, often through traditional hemodialysis. However, this can lead to rapid serum sodium correction, potentially causing neurological complications. We present a case of a CKD patient with a suspected stroke, who exhibited dizziness, confusion, and an unsteady gait, and was found to have azotemia, metabolic acidosis, and severe hyponatremia (101 mmol/L). We managed the case by gradually correcting the serum sodium with hypertonic saline. Subsequently, we initiated traditional hemodialysis using a dialysate sodium concentration of 130 mEq/L when the serum sodium levels increased to 122 mmol/L. The patient was discharged in a vitally and hemodynamically stable condition, with a serum sodium level of 137 mmol/L. This report highlights the intricacies of managing severe hyponatremia in a CKD patient with a suspected stroke.

Implication for health policy/practice/research/medical education:

In this case report, we found, slow and gradual correction of serum sodium and subsequent use of traditional hemodialysis with low sodium dialysate offers a viable strategy to manage chronic kidney disease patients with severe hyponatremia.

Please cite this paper as: Qasem A, Rabbani SA, Kurian MT, Sridhar SB. Management of severe hyponatremia in a chronic kidney disease patient; a case report. J Nephropharmacol. 2024;13(2):e11674. DOI: 10.34172/npj.2024.11674.

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