Society of Diabetic Nephropathy Prevention Journal of Nephropharmacology 2345-4202 7 1 2018 01 01 The relationship between low-birth weight and nephrotic syndrome in children 6 9 10.15171/npj.2018.03 EN Negin Rezavand Abolhassan Seyedzadeh Mohammad-Reza Tohidi Mohammad-Saleh Seyedzadeh Sara Hookary Alireza Abdi Journal Article 10.15171/npj.2018.03 2017 08 20 2017 11 14 Introduction: The body weight of an infant is one of the most important factors that influences its survival, growth and development. Many clinical studies have shown a higher risk of an aggravated course of renal disease in children born with low- birth weight (LBW), due to reduction in glomerular number and development. However, there are limited clinical studies about this relationship. Results: This study revealed that the risk of nephrotic syndrome in patients with LBW is two times higher than those with normal birth weight. However, there was no statistically significant difference (χ2 = 1.58, P = 0.12) Conclusion: Although the result of this study cannot show a statistically significant relationship between INS and LBW, the risk of nephrotic syndrome was twice in the case group.