Society of Diabetic Nephropathy Prevention Journal of Nephropharmacology 2345-4202 6 2 2017 04 01 Calcium-vitamin D supplementation; does it affect lipid profile of menopaused women with normal renal function? 74 78 10.15171/npj.2017.08 EN Maryam Javadian Shahla Yazdani Karimollah Hajian-Tilaki Roya Gharouei Journal Article 10.15171/npj.2017.08 2017 02 05 2017 04 10 Introduction: The association between dyslipidemia and cardiovascular disease in women has been proposed and many studies investigated calcium-vitamin D (CaD) supplementation and their effect on lipid concentrations. Objectives: This randomized single-blind study aimed to evaluate the effect of CaD supplementation on serum lipid levels of menopaused women with normal renal function. Results: One hundred women with average age of 62.76 ± 7.02 years and BMI of 27.98 ± 3.44 kg/m2 were enrolled. FBS, cholesterol, HDL-C and LDL-C of the patients significantly increased (P < 00.001) but the mean TG and LDL/HDL ratio significantly decreased (P < 00.001). Also, the difference in LDL/HDL ratio was not significant after 3 months, but it was significant after 6 months (P = 00.155 and P < 00.001, respectively). Conclusion: Supplemental CaD significantly increased HDL-C and decreased TG and LDL/HDL ratio. Thus, it is recommended in menopaused women.