Society of Diabetic Nephropathy Prevention Journal of Nephropharmacology 2345-4202 13 2 2024 06 29 Antihypertensive effects of SGLT2 inhibitors; a letter to the editor on new concepts e12700 e12700 10.34172/npj.2024.12700 EN Rahimeh Eskandarian https://orcid.org/0000-0002-4727-3386 Mohammad Memarian https://orcid.org/0000-0003-4534-3018 Samira Mehrabi Pari https://orcid.org/0000-0003-2395-5830 LETTER 10.34172/npj.2024.12700 2024 05 04 2024 06 07 SGLT2 inhibitors, primarily used to treat diabetes, have shown potential antihypertensive effects by reducing blood pressure through mechanisms like natriuresis, diuresis, and weight loss. These medications may also improve arterial stiffness and reduce inflammation, impacting to their blood pressure-lowering properties.