Society of Diabetic Nephropathy Prevention Journal of Nephropharmacology 2345-4202 12 1 2023 01 01 COVID-19-associated thrombotic thrombocytopenic purpura (TTP); a case report e10454 e10454 10.34172/npj.2022.10454 EN Ali Hajigholami https://orcid.org/0000-0001-6467-2971 Hourieh Ansari https://orcid.org/0000-0002-2468-5345 Sakineh Ansari https://orcid.org/0000-0001-7069-2178 Shakiba Hassanzadeh https://orcid.org/0000-0002-5091-5191 Journal Article 10.34172/npj.2022.10454 2021 10 17 2021 12 01 The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or coronavirus disease (COVID-19) pandemic is the largest infectious crisis in the present century. It has been reported that COVID-19 infection may trigger autoimmune diseases. Herein, we report a 68-year-old male that was diagnosed with thrombotic thrombocytopenic purpura (TTP) following COVID-19 infection. To our knowledge, this is the fourth case of COVID-19-associated TTP. More attention is required regarding the possibility of developing TTP in COVID-19 patients, especially with the presence of decreased consciousness and low levels of hemoglobin and platelet.