Society of Diabetic Nephropathy Prevention Journal of Nephropharmacology 2345-4202 2 2 2013 04 01 Significance of diet in chronic kidney disease 37 43 EN Chaudhary Muhammad Junaid Nazar Journal Article It is obvious that malnutrition is extremely dominant in end-stage renal disease (ESRD) patients. Malnutrition in pre-dialysis, dialysis, and post-dialysis stages is related to multiple factors. However, research work shows that if we try to improve the poor nutrition status of ESRD patients, good clinical outcomes may result. But the long-term effect of nutrition in the presence of other comorbid conditions has not been well established by many studies. So this aspect of nutrition is still researchable. Some studies emphasise that malnutrition is a major comorbid condition in ESRD victims as are hypertension, diabetes mellitus (DM) and cardiovascular disease. Researchers believe that the nutritional status, treatment and diagnostic parameters of these patients should be altered to achieve progress not only in their mortality outcome, but also in their quality of life