Introduction: Chronic kidney disease (CKD) in advanced stages leads to some changes in
lifestyle, health status, and personal functioning and consequently affects the patients’ quality
Objectives: Given the high prevalence of CKD in the country, this study aimed to determine
quality of life and its related factors in this group of patients. Since there has been low focus
on quality of life in pre-dialysis stage, this study compared the two groups of pre-dialysis and
hemodialysis patients regarding quality of life.
Patients and Methods: This descriptive analytical research was conducted as a cross-sectional
study. Using convenience sampling method, we selected a total of 60 kidney failure patients in
pre-dialysis stage that referred to nephrology clinics in Semnan and 60 hemodialysis patients
who referred to the dialysis center of Kosar hospital in Semnan. Using SF-36 questionnaire and
a demographic form, the required data was collected via interviews.
Results: The results showed that the majority of patients had a moderate quality of life.
Concerning demographic variables, quality of life had a significant relationship with age,
gender, marital status, number of children, employment status, education level, income level,
hemoglobin, underlying disease, duration of disease, and duration of dialysis. Moreover,
patients in pre-dialysis stage had a better score than hemodialysis patients regarding the
overall quality of life (P≤0.05).
Conclusion: This study showed, a design a framework for care services provided by medical
staffs and supports provided by insurance organizations and other institutions is necessary.
The framework must help to improve quality of life of patients and prevent the deterioration
of quality of life in advanced stages of the disease.